Taking antibiotics during pregnancy can cause the lung disease of the newborn
Source:a Baby born at 23 weeks can easily fit into the palm of your hand and weighs just about 500 grams
As you know, the average duration of pregnancy is about 40 weeks or 280 days. In medical practice, consider the baby full term in that case, if he was born from 38 to 42 weeks of pregnancy, however, absolutely at any time there is a risk of premature births, which carry a greater threat for whose vital organs are not yet ready for independent functioning outside the womb. Fortunately, with the development of medical technology, professionals can improve the chances of survival of babies born after 23 weeks of fetal development. However, scientists have found that taking antibiotics during pregnancy significantly reduces the chance of survival of a premature baby because of his syndrome pulmonary dysplasia.
How do antibiotics affect the survival of newborns?
Thanks to the progress in the development of neonatology, doctors can save even the most extremely premature baby, providing it with the necessary therapy for the subsequent development. But in spite of thorough medical care of premature babies, they still experience various serious diseases. Due to lack of development in premature infants lung scarring and inflammation develops. Lung damage at an early stage of development leads to chronic , which is called — bronchopulmonary dysplasia. This disease is one of the most severe and prolonged complications in preterm children, which may follow them throughout life.
Researchers found that the disease is directly related to oxygen and breathing apparatus with which the professionals provide the vital functions of an organism of the child. In the study, and pneumonia, researchers found that causing the inflammation are pathogenic and colonize the intestinal flora. The reason for exceeding the number of microorganisms that caused inflammation in the body can become weakened immunity.
the child born long before the supposed date of the birth, there is a high probability of disability
In order to identify the causes because of which the subsequently developing bronchopulmonary dysplasia in children, scientists have tried to identify events that could affect the child's development in the womb. It turned out that one of the possible causes of the disease could be antibiotics. Scientists discovered that mothers who during pregnancy were exposed to , most of the children were born with bronchopulmonary dysplasia. But test and prove this relationship in the person, the scientist is not yet possible. That is why the experts conducted a study on mice, during which they tried to identify a causal link between and disease.
According to an article published on the portal , the purpose of the experiment was to study the effects of antibiotics on lung development in the offspring. For this, the researchers separated pregnant mice into four groups depending on pregnancy. The first group was exposed to antibiotics during the entire pregnancy and during the first two weeks after birth. The second group of mice were exposed only during pregnancy, in the third group worked only during feeding, and the fourth was used as control and did not apply to her antibiotics.
After the birth of the offspring, of mice exposed to oxygen by analogy to premature human infants after birth, causing the possible development of bronchopulmonary dysplasia. The result of the experiment revealed that all newborn mice to some extent, developed bronchopulmonary dysplasia, but in mice whose mothers were exposed to more prolonged exposure to antibiotics, the disease developed in the most severe.
the Effects of antibiotics resulted in a more severe form of bronchopulmonary dysplasia in mice
Presumably, the antibiotics could affect the microbiome of the mother, causing the changes subsequently inherited by offspring. Thus, the immune cells of newborns could not resist developing pathology due to the initial weakness of the body's defenses. Thus, currently, scientists do not recommend antibiotics for pregnant women, however, in the absence of alternative treatments, doctors need to consider all risks, not only for mother but also fetus.
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