Microbes, slow one antibiotic develops resistance to others

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2020-01-21 01:40:07

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Superbugs can do today a deadly curable diseases

Not completely wiped out infectious bacteria, as it turned out, can be more dangerous than previously thought. According to a study published in the journal , even if one antibiotic leads to inaction bacteria further germs almost three times faster develop resistance to the other drug. The value of the findings today cannot be understated — according to a statement from the world health organization, the emergence of resistant superbugs is one of the main threats facing humanity.

Why is it necessary to drink antibiotics only by prescription?

If you are still self medicating and throwing antibiotics at the slightest sore throat — urgent stop. The fact that the uncontrolled use of antibiotics has led to the emergence of the so-called — microbes that have acquired a tolerance to a particular drug. Data from a recent study once again emphasize that scientists need to pay close attention to what is happening with the bacteria. It turned out that in the presence of antibiotics, the bacteria cease to multiply, turning into a kind of dormant state, which helps the microbes to withstand attack medications longer than usual. To counteract antibiotic tolerant germs can not, therefore, simply “give up”. However, it is not completely lost. With the exception of cases in which the impact of the antibiotic in large doses is ongoing, if the resistance of bacteria to them is not increased.

What does this mean for patients?

This tolerant bacteria can be a source of prolonged or repeated infections and mainly affects individuals with a weakened immune system, as well as people with medical implants. To defeat the spread of infection, doctors can give patients the drug cocktails. Especially doing so with tuberculosis, which in recent years has become difficult to beat. According to the publication , according to previously conducted studies, the tolerant are more likely to develop resistance to antibiotics. Today, similar cases in medical practice has become increasingly common. Recently, doctors used a powerful antibiotic vancomycin for the treatment of two patients admitted in the period from may 2017 to may 2018 in the hospital Xagħra-Tzedek in Jerusalem. Both patients in the blood were identified methicillin-resistant Staphylococcus aureus. After a few days of antibiotics, bacteria have acquired a tolerance to the drug.

it looks like under a microscope antibiotic resistant Staphylococcus aureus

Similar results were obtained in laboratory experiments with the bacteria Escherichia coli, treated with several different combinations of drugs. These results probably indicate that tolerance can lead to resistance to a broad spectrum of bacteria. And tolerance, in turn, leads to the emergence of bacteria resistance to antibiotics. The way out of the situation the researchers call for immediate treatment with several drugs simultaneously to avoid developing of bacterial tolerance and resistance. However, it is not so simple as it might seem at first glance. Such shock doses of antibiotics can also destroy the immune system of patients. And along with a large number , cost of drugs and other factors, this option looks more suitable.

Unfortunately, to date, experts do not know how to deal with the growing tolerance of bacteria to various antibiotics. However, while scientists continue to conduct clinical trials, we must each adhere to the gold, at present, the rule — should be taken solely on prescription. Don't forget that self-medicate, you endanger not only yourself and your loved ones, but also all the inhabitants of our planet.

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